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Science Focus - Term 1

 

Marwa Mohammed & Shahd Wael

How AI is Revolutionizing Biology

How AI Became Biology’s New MVP


Explore with Marwa Mohamed and Shahd Wael how AI is transforming science!

Imagine a world where diseases like cancer or Alzheimer’s can be cured before they even develop, thanks to an incredible machine solving one of biology’s hardest puzzles. Meet AlphaFold, the AI that’s changing science.

Did you know the scientists, Demis Hassabis and John jumper, creators of AlphaFold, revolutionized science? And David Baker who has learned how to master life's building blocks and create entirely new proteins!


The Role of AlphaFold

AlphaFold, developed by Google DeepMind and Isomorphic Labs, uses machine learning to predict protein structures with great accuracy. It analyzes vast datasets of protein structures to identify patterns in how amino acids work, but proteins are dynamic, always moving and changing shape. AlphaFold could miss details about proteins in action because it predicts static structures.

Fun Fact: One thing you should know, predicting the structure of a protein is exactly like solving a Rubik’s cube in the dark. AlphaFold is like the light shining on the cube revealing the colors, making it solvable.


What Are Proteins, and Why Do They Matter?

Proteins — the building blocks of life. Made from long chains of amino acids, which can fold into countless possible 3D shapes by the laws of thermodynamics and energy minimization. A typical protein has thousands of atoms, and the way they interact determines its final structure. Proteins rely on chemical interactions like hydrogen bonds, ionic bonds, and hydrophobic bonds.

Proteins matter because they are the foundation of life itself, being responsible for nearly every function in living organisms.


Why is Predicting Protein Structures Important?

It’s important for understanding diseases, as many diseases are caused by misfolded proteins. By knowing their structure, our scientists can: develop medicine, create vaccines faster, and engineer proteins to solve global challenges.

Keep in mind, this process was a major unsolved challenge in science before the release of AlphaFold.

AlphaFold is already making huge impacts, but the journey doesn't end here, as scientists will keep on working on it. This could inspire the next generation of biologists, maybe even you!